In vitro study | BMS-833923 reduces hedgehog pathway activity, reduces cell proliferation, and induces apoptosis in esophageal adenocarcinoma (EAC) cell lines via an endogenous pathway. In vitro, BMS-833923 dose-dependently affects typical and prostate hedgehog signaling gene transcription. BMS-833923 decreases hedgehog pathway activity, reduces cell proliferation, and induces apoptosis in esophageal adenocarcinoma (EAC) cell lines via an endogenous pathway. In vitro, BMS-833923 dose-dependently affects typical and prostate hedgehog signaling gene transcription. |